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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

1. A patient with severe combined immunodeficiency (SCID) develops a progressive respiratory illness.
Bronchoalveolar lavage fluid is examined using direct fluorescent antibody (DFA) staining, which reveals numerous cysts of Pneumocystis jirovecii. The cysts appear:

A) Small and round with a thick wall, containing sporozoites.
B) Oval-shaped with a thin wall and internal nuclei.
C) Large and multinucleated with prominent endospores.
D) Cup-shaped or helmet-shaped with internal structures.

2. Staphylococcus epidermidis, a common cause of healthcare-associated infections, forms biofilms on medical devices. The production of polysaccharide intercellular adhesin (PIA) is a key factor in biofilm maturation.
The expression of PIA is primarily regulated by:

A) A two-component regulatory system involving AgrA and AgrC.
B) The icaADBC operon, whose expression is influenced by environmental cues.
C) The stringent response pathway activated during nutrient limitation.
D) Horizontal gene transfer of the ica operon.

3. A clinical microbiology laboratory is implementing a new laboratory information system (LIS). A critical step in the validation process is ensuring the accurate and reliable transfer of data, including patient demographics, test orders, and results. This aspect of validation primarily focuses on:

A) Analytical sensitivity and specificity.
B) Workflow efficiency and user training.
C) Clinical sensitivity and specificity.
D) Data integrity and interoperability.

4. An elderly patient in a long-term care facility develops a localized outbreak of painful vesicles along a dermatome. Tzanck smear of a vesicle reveals multinucleated giant cells. The MOST likelycausative agent is:

A) Coxsackievirus
B) Orf virus
C) Varicella-zoster virus
D) Herpes simplex virus type 1

5. A patient with cystic fibrosis experiences a pulmonary exacerbation. Sputum culture grows a mucoid strain of Pseudomonas aeruginosa. The mucoid phenotype is primarily due to the overproduction of:

A) Elastase
B) Exotoxin A
C) Pyocyanin
D) Alginate

Solutions: